Medical Disclaimer: This is educational content only, not medical advice. Consult a licensed healthcare provider for diagnosis/treatment. Information based on sources like WHO/CDC guidelines (last reviewed: 2026-02-13).
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Medical Disclaimer: This is educational content only, not medical advice. Consult a licensed healthcare provider for diagnosis/treatment. Information based on sources like WHO/CDC guidelines (last reviewed: 2026-02-13).
The breast is a modified apocrine sweat gland, also known as the mammary gland, specialized for milk production and lactation in females.
The breast lies in the superficial fascia of the anterior chest wall, extending from the 2nd to the 6th rib and from the lateral border of the sternum to the mid-axillary line.
The axillary tail, also called the Tail of Spence, is a lateral extension of breast tissue into the axilla and is clinically important in breast cancer spread.
A normal adult breast contains approximately 15–20 lobes arranged radially around the nipple.
Cooper’s ligaments are fibrous connective tissue bands that extend from the skin to the deep fascia, helping maintain the shape and structural integrity of the breast.
The nipple contains openings of lactiferous ducts and serves as the exit point for milk during lactation.
Adipose (fat) tissue is absent beneath the nipple and areola.
The breast receives blood from the internal thoracic artery, lateral thoracic artery, thoracoacromial artery, and posterior intercostal arteries.
Approximately 75% of breast lymph drains into the axillary lymph nodes, especially the anterior (pectoral) group.
Sappey’s plexus is a subareolar lymphatic network that plays a key role in lymph drainage from the nipple and areola.
The nipple is mainly supplied by the fourth intercostal nerve (T4).
The retromammary space is a loose connective tissue plane between the breast and pectoral fascia that allows free mobility of the breast.
The breast develops from the mammary ridge, also known as the milk line.
Polymastia refers to the presence of accessory breast tissue, usually occurring along the milk line.
During pregnancy, estrogen promotes ductal growth while progesterone stimulates lobuloalveolar development.
Prolactin is responsible for milk production in the alveoli of the breast.
Oxytocin causes contraction of myoepithelial cells leading to milk ejection.
Breast carcinoma spreads easily due to rich lymphatic drainage and absence of a well-defined deep fascial barrier.
Peau d’orange occurs due to lymphatic obstruction leading to skin edema and pitting.
Gynecomastia is the benign enlargement of male breast tissue due to hormonal imbalance, particularly increased estrogen activity.
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