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Depression Treatment Guide Symptoms Causes Therapy Medications and Recovery

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Frequently Asked Questions

What is depression?

Depression is a mental health disorder characterized by persistent sadness, loss of interest, fatigue, poor concentration, sleep disturbances, and reduced daily functioning lasting at least two weeks.

What are the main symptoms of depression?

Symptoms include low mood, loss of interest, hopelessness, guilt, fatigue, appetite changes, sleep problems, poor concentration, and suicidal thoughts.

What causes depression?

Depression can be caused by genetic factors, brain chemical imbalance, stressful life events, trauma, chronic illness, substance use, and hormonal changes.

How is depression diagnosed?

Depression is diagnosed through clinical interviews, symptom duration assessment, psychiatric evaluation, and standardized screening tools based on DSM-5 criteria.

What are the main treatments for depression?

Treatment includes psychotherapy, antidepressant medications, lifestyle changes, social support, and advanced therapies like ECT or TMS in severe cases.

Which medications are commonly used to treat depression?

Common antidepressants include SSRIs, SNRIs, bupropion, mirtazapine, tricyclic antidepressants, and MAO inhibitors depending on patient response.

How long do antidepressants take to work?

Most antidepressants take 2 to 6 weeks to show noticeable improvement, with full benefits often seen by 8 to 12 weeks.

Can depression be treated without medication?

Yes, mild to moderate depression can often be managed with psychotherapy, lifestyle changes, exercise, sleep improvement, and stress management.

What is treatment-resistant depression?

Treatment-resistant depression refers to depression that does not respond to at least two adequate trials of antidepressant medications.

When is Electroconvulsive Therapy (ECT) used?

ECT is used in severe, psychotic, suicidal, or medication-resistant depression where rapid symptom improvement is needed.

Can depression increase suicide risk?

Yes, untreated depression significantly increases the risk of suicidal thoughts, suicide attempts, and self-harm.

How long should depression treatment continue?

Treatment should continue for at least 6 to 12 months after symptom remission, and longer in recurrent cases.

Is depression curable?

Depression is highly treatable, and many patients achieve full remission with proper medical and psychological care.

What lifestyle changes help in depression recovery?

Regular exercise, good sleep, healthy diet, stress management, social engagement, avoiding alcohol, and structured daily routines support recovery.

What are warning signs of severe depression?

Warning signs include persistent suicidal thoughts, inability to function, psychotic symptoms, severe withdrawal, and refusal to eat or drink.

Can teenagers and children get depression?

Yes, depression affects children and adolescents, often presenting with irritability, academic decline, social withdrawal, and self-harm behavior.

Does depression come back after treatment?

Depression can relapse, especially if treatment is stopped early, but long-term therapy and lifestyle management reduce recurrence.

What is the difference between depression and sadness?

Sadness is temporary, while depression is persistent, more severe, affects daily life, and lasts for weeks or months.

Can depression be prevented?

Risk can be reduced through stress management, emotional support, healthy lifestyle, early intervention, and mental health awareness.

When should someone seek professional help for depression?

Professional help should be sought if symptoms last more than two weeks, worsen over time, interfere with daily life, or involve suicidal thoughts.

MCQ Test - Depression Treatment Guide Symptoms Causes Therapy Medications and Recovery

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1 A 35-year-old woman reports persistent low mood, loss of interest, fatigue, guilt, insomnia, and poor concentration for 3 months with functional impairment. No history of mania. What is the most likely diagnosis?

Explanation:

Symptoms lasting more than 2 weeks with impaired functioning and no manic episodes meet criteria for Major Depressive Disorder.

2 A 50-year-old man with depression has early morning awakening, weight loss, psychomotor retardation, and excessive guilt. This pattern suggests which subtype?

Explanation:

Melancholic depression is marked by anhedonia, early morning awakening, weight loss, and guilt.

3 A patient on SSRI therapy develops agitation, sweating, tremor, confusion, hyperthermia, and diarrhea. What is the most likely diagnosis?

Explanation:

Serotonin syndrome occurs due to excessive serotonergic activity and presents with autonomic instability and neuromuscular symptoms.

4 A 29-year-old man with depression reports active suicidal ideation and a prior suicide attempt. What is the best immediate management?

Explanation:

High suicide risk requires urgent inpatient psychiatric admission for safety.

5 A patient reports hypersomnia, increased appetite, weight gain, mood reactivity, and rejection sensitivity. This presentation is most consistent with?

Explanation:

Atypical depression features hypersomnia, hyperphagia, and interpersonal sensitivity.

6 A depressed patient treated with antidepressants develops elevated mood, decreased need for sleep, grandiosity, and impulsive behavior. What is the most likely explanation?

Explanation:

Antidepressants can precipitate mania in undiagnosed bipolar disorder.

7 A severely depressed patient with psychotic delusions refuses food and fluids. What is the most effective immediate treatment?

Explanation:

ECT is life-saving in severe, psychotic, or treatment-resistant depression.

8 An elderly patient with depression presents with memory complaints and cognitive slowing that improve with treatment. What is the most likely diagnosis?

Explanation:

Depressive pseudodementia mimics dementia but improves with antidepressant therapy.

9 A woman develops severe depression with intrusive thoughts of harming her newborn within weeks after delivery. What is the most likely diagnosis?

Explanation:

Intrusive thoughts of harming the infant indicate postpartum psychosis.

10 A patient has chronic low mood, low energy, and poor self-esteem for 3 years with no symptom-free period longer than 2 months. What is the diagnosis?

Explanation:

Dysthymia involves chronic depressive symptoms lasting at least 2 years.

11 A patient with depression does not improve after two adequate antidepressant trials. What is the next best step?

Explanation:

Treatment-resistant depression requires switching drugs or augmentation strategies.

12 A suicidal patient reports access to lethal means and has a detailed suicide plan. What is the most appropriate immediate action?

Explanation:

Imminent suicide risk requires emergency hospitalization and constant monitoring.

13 A patient with depression and alcohol dependence seeks treatment. What is the most appropriate management?

Explanation:

Integrated treatment of co-occurring disorders improves outcomes.

14 A patient reports depressive episodes occurring only during winter months with remission in summer. What is the most likely diagnosis?

Explanation:

Seasonal affective disorder follows a seasonal pattern, commonly winter-related.

15 A patient with severe depression, nihilistic delusions, and auditory hallucinations requires treatment. What is the best approach?

Explanation:

Psychotic depression requires combined antidepressant and antipsychotic therapy.

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